【摘 要】
：
A gram scale approach was developed toward the advanced intermediate of taiwaniaquinoids.This intermediate 5a with trans A/B ring junction was concisely assembled by employing a Bi(OTf)3-catalyzed cat
【机 构】
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State Key Laboratory of Bioorganic and Natural Products Chemistry,Shanghai Institute of Organic Chem
【出 处】
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The 24th International Society of Heterocyclic Chemistry Con
论文部分内容阅读
A gram scale approach was developed toward the advanced intermediate of taiwaniaquinoids.This intermediate 5a with trans A/B ring junction was concisely assembled by employing a Bi(OTf)3-catalyzed cationic cyclization and a Wolff-type ring contraction as key steps.The above sequence scaled reliably, and 1 g of 5a was readily prepared.This common intermediate was readily converted to racemic taiwaniaquinones A and F and taiwaniaquinols B and D, respectively.
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