Drosophila offers enormous advantage in deciphering gene functions and pathways.The past 30 years have witnessed numerous translation examples offindings originally made in Drosophila to many other areas of biomedical research.These researches greatly facilitated our fundamental understanding of some biological processes,including ertain key human diseases such as cancer and neurodegenerative diseases.We thus consider Drosophila will provide a different perspective and complement our existing strategies of trace element research.