【摘 要】
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Background, Motivation and Objective Angiogenesis is a critical feature of plaque development in atherosclerosis and might play a key role in the eventual rupture of plaques. The precursory molecular
【机 构】
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Thoraxcenter Biomedical Engineering, Erasmus MC, Rotterdam, Netherlands
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Background, Motivation and Objective Angiogenesis is a critical feature of plaque development in atherosclerosis and might play a key role in the eventual rupture of plaques. The precursory molecular or cellular events that initiate plaque growth and that ultimately contribute to plaque instability, however, cannot be detected directly with any current diagnostic modality. This study is designed to investigate the feasibility for molecular imaging of endothelial αvβ3 expression in vitro and in vivo using the αvβ3-targeted ultrasound contrast agents (UCA).
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