20年间在本院住院的2904例系统性红斑狼疮患者中,有3例以心包填塞为首发症状,均为中年女性,大量心包积液,蛋白含量高,病理为慢性非特异性炎症,糖皮质激素及免疫抑制剂治疗反应良好,未复发心包填塞。对以心包填塞为首发症状的患者,应考虑到系统性红斑狼疮的可能性,心包积液的检查对于明确诊断及治疗具有重要意义。 Among 2 2904 patients with systemic lupus erythematosus hospitalized in our hospital in 20 years, 3 cases were treated with tamponade as the first symptom. All of them were middle-aged women with a large amount of pericardial effusion, high protein content, pathological chronic nonspecific inflammation, Hormone and immunosuppressive agents responded well and did not recurrent pericardial stuffing. To tamponade as the first symptom of patients should take into account the possibility of systemic lupus erythematosus, pericardial effusion of the examination for the diagnosis and treatment of great significance.