【摘 要】
：
The production of 20-hydroxyeicosatetraenoic acid (20-HETE) is increased during ischemia-reperfusion, and inhibition of 20-HETE production has been shown to reduce infarct size caused by ischemia.This
【机 构】
：
Northeast Normal University China
【出 处】
：
BITs 2rd Annual World Cancer Congress of Cardiology-2010(201
论文部分内容阅读
The production of 20-hydroxyeicosatetraenoic acid (20-HETE) is increased during ischemia-reperfusion, and inhibition of 20-HETE production has been shown to reduce infarct size caused by ischemia.This study was aimed to discover the molecular mechanism underlying the action of 20-HETE in cardiac myocytes.The effect of 20-HETE on L-type Ca2+ currents (ICa,L) was examined in rat isolated cardiomyocytes by patch-clamp recording in the whole cell mode.
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