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目的研究康妇炎胶囊的抗炎、镇痛作用。方法通过二甲苯致小鼠耳廓肿胀、醋酸致小鼠腹腔毛细血管通透性和琼脂致小鼠皮下肉芽肿实验观察康妇炎胶囊的抗炎作用,采用热板法和扭体法观察其镇痛作用。结果康妇炎胶囊能够显著抑制二甲苯所致小鼠耳廓肿胀,显著降低小鼠腹腔毛细血管通透性,抑制小鼠皮下肉芽肿的形成;并明显降低热刺激所致的小鼠痛阈值,减少小鼠的扭体次数。结论康妇炎胶囊对炎症有明显的抑制作用,且有一定的镇痛效果。
Objective To study the anti-inflammatory and analgesic effect of Kang Fu Yan Capsule. Methods The anti-inflammatory effect of Kangfeiyan capsule was observed by xylene-induced auricle swelling in mice, peritoneal capillary permeability induced by acetic acid in mice, and subcutaneous granuloma induced by agar in mice. The anti-inflammatory effects of Kangfeiyan capsule were observed by hot plate method and writhing method Analgesic effect. Results Kangfeiyan capsule can significantly inhibit xylene-induced ear swelling in mice, significantly reduce the peritoneal capillary permeability in mice, inhibit the formation of subcutaneous granuloma in mice; and significantly reduce the thermal stimulation induced mice pain threshold , Reduce the number of wrists in mice. Conclusion Kangfeiyan capsule has a significant inhibitory effect on inflammation, and has some analgesic effect.