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目的 探讨新生儿缺氧缺血性脑病 (HIE)患儿血清中细胞因子水平及其临床意义。方法 对 32例新生儿缺氧缺血性脑病患儿血清中 IL - 6、TNF-α的水平进行检测。结果 血清中 IL - 6、TNF-α含量明显高于对照组 (P<0 .0 1)。结论 检测血清中 IL - 6、TNF-α含量可作为判断 HIE患儿预后 ,恢复程度及指导治疗的指标
Objective To investigate the serum levels of cytokines in neonates with hypoxic-ischemic encephalopathy (HIE) and its clinical significance. Methods Serum levels of IL - 6 and TNF - α in 32 neonates with hypoxic - ischemic encephalopathy were measured. Results Serum levels of IL - 6 and TNF - α were significantly higher than those of the control group (P <0.01). Conclusion Detection of IL - 6 and TNF - α in serum can be used as an index to judge prognosis, degree of recovery and guiding therapy in children with HIE