酰胺型萃取剂N-503[N,N-二-(1-甲基庚基)乙酰胺]可以用甲庚醇或2-氯代辛烷为原料来合成。它的重要中间体二-(1-甲基庚基)胺的制备方法有二:一是从甲庚醇制备的方法,将甲庚醇用阮来镍催化,常压氨解,得率95～99％左右;二是从2-氯代辛烷制备,此法需要高压设备,得率35％左右。第一个方法在扩大试验中,产率和产品质量都比较好,是一个较好的制备长碳链仲胺的方法。 Amide extractant N-503 [N, N-di- (1-methylheptyl) acetamide] can be synthesized starting from heptanol or 2-chlorooctane. Its important intermediates di - (1-methylheptyl) amine preparation methods are two: First, from the method of preparation of heptanol, n-heptanol with nickel catalyst, atmospheric ammonia solution, the yield of 95 to 99 %; Second is from 2-chloro-octane preparation, this method requires high-pressure equipment, yield of about 35%. The first method in the expansion of the test, the yield and product quality are better, is a better preparation of long carbon chain secondary amine method.