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目的: 研究人参多糖治疗恶性胸腔积液疗效及其毒副作用。方法: 20 例患者皆经病理证实有恶性胸腔积液,病种分布为乳癌、肺癌、恶性间皮瘤和胃癌,人参多糖剂量为36 ~60 mg/ 次胸腔注射,每周一次,连用1 ~2 周。结果: 人参多糖对恶性胸腔积液的有效率为75 % ,并可增强 T 淋巴细胞及 N K 细胞活性。不良反应为一过性体温升高,最高为38 .5 ℃,无其他毒副作用发生。结论: 人参多糖可用于恶性胸腔积液的治疗。
Objective: To study the efficacy and side effects of ginseng polysaccharide in the treatment of malignant pleural effusion. METHODS: Twenty patients were pathologically confirmed to have malignant pleural effusions. The lesions were distributed in breast cancer, lung cancer, malignant mesothelioma and gastric cancer. The dose of ginseng polysaccharide was 36 to 60 mg/time of intrapleural injection once a week for 1 to 1 consecutive days. 2 weeks. Results: The effective rate of ginseng polysaccharide in malignant pleural effusion was 75%, and it could enhance the activity of T lymphocytes and N K cells. The adverse reaction was a transient increase in body temperature, with a maximum of 38. 5 °C, no other toxic side effects occurred. Conclusion: Ginseng polysaccharide can be used for the treatment of malignant pleural effusion.