论文部分内容阅读
目的小剂量氯胺酮静脉复合麻醉对剖宫产新生儿的影响。方法Ⅰ组(实验组):选择有硬膜外麻醉禁忌证剖宫产病人30例,采用小剂量氯胺酮复合咪达唑仑麻醉:咪达唑仑0.04mg/kg,氯胺酮0.5mg/kg静脉注射,胎儿娩出后,酌情追加氯胺酮、异丙酚维持麻醉。Ⅱ组(对照组)30例:Ⅰ组每例后第1例硬膜外麻醉剖宫产组成。观察两组麻醉效果、不良反应、BP、HR、SpO2、新生儿脐带血气分析及新生儿Apgar评分。结果两组麻醉方法均能满足手术要求,Ⅰ组病人均不能回忆手术经过,无呕吐发生,两组脐带血气分析及新生儿Apgar评分无显著性差异(P>0.05),硬膜外麻醉组血流动力学改变显著(P<0.05)。结论小剂量氯胺酮复合咪达唑仑静脉麻醉能满足剖宫产手术要求,对新生儿无明显影响。
Objective To investigate the effect of low dose ketamine intravenous anesthesia on cesarean newborn. Methods Group I (experimental group): 30 cases of cesarean section were selected contraindications to epidural anesthesia, midazolam combined with low dose of midazolam anesthesia: midazolam 0.04mg / kg, ketamine 0.5mg / kg intravenous injection , After the baby was delivered, as appropriate, add ketamine, propofol to maintain anesthesia. Ⅱ group (control group) 30 cases: Ⅰ group after each case of epidural anesthesia cesarean section. The anesthetic effects, side effects, BP, HR, SpO2, neonatal umbilical cord blood gas analysis and neonatal Apgar scores were observed. Results The anesthesia of both groups could meet the requirements of operation. All the patients in group Ⅰ could not recall the operation and no vomiting. There was no significant difference between the two groups in blood gas analysis and neonatal Apgar score (P> 0.05) Flow dynamics changed significantly (P <0.05). Conclusion Low-dose ketamine combined midazolam intravenous anesthesia can meet the requirements of cesarean section surgery, no significant effect on newborns.