论文部分内容阅读
目的比较平坦型腺瘤和隆起型腺瘤的临床病理学特征,探讨两者生物学行为的差异。方法选取2002年至2006年间行结肠镜检查并经病理证实的平坦型和隆起型腺瘤,比较两者的病理学特征差异。结果平坦型和隆起型腺瘤重度异型增生的构成比分别为12.91%(4/31)和2.31%(12/519),在直径≤2.0 cm的腺瘤中,发生重度异型增生的比例分别为14.81%(4/27)和1.07%(5/466),两组比较统计学差异均有显著性(P<0.01,P<0.01)。结论平坦型腺瘤发生重度异型增生的比例较隆起型腺瘤高,而且可能在体积更小时出现异型增生,提示平坦型腺瘤的生物学行为与隆起型腺瘤不同,平坦型腺瘤可能具有更高的恶变倾向。
Objective To compare the clinicopathological characteristics of flat adenoma and adenohypophysis, and to explore the difference of their biological behavior. Methods From 2002 to 2006, we selected colon biopsies and pathologically confirmed flat and elevated adenomas, and compared their pathological features. Results The proportions of severe dysplasia were 12.91% (4/31) and 2.31% (12/519), respectively. The proportion of severe dysplasia in adenomas ≤2.0 cm were 14.81% (4/27) and 1.07% (5/466), respectively. There was significant difference between the two groups (P <0.01, P <0.01). Conclusions The proportion of severe dysplasia in the flat adenoma is higher than that in the adenoid adenoma, and the dysplasia may occur when the volume is smaller. It suggests that the biological behavior of the flat adenoma is different from that of the adenoid adenoma, and the flat adenoma may have Higher malignant tendency.