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目的观察新疆高血压住院人群中原发性醛固酮增多症的状况,从而为继发性高血压的检出提供流行病学支持。方法选取1997年-2005年所有高血压专科的住院患者4 642例,其中原发性醛固酮增多症患者83例,其诊断标准采用:手术病理证实。原发性高血压患者4 095例。均按照1999年中国高血压指南诊断标准确诊。统计学方法采用95%可信区间(95%CI)及t检验。结果在新疆高血压人群中原发性高血压的检出率为88%(87.4%,89.3%),在不同民族间哈萨克族检出率最高92%(97.7%,96.6%);原发性醛固酮增多症的检出率为2%(1.4%,2.2%),其中男性为2%(1.7%,2.9%),女性1%(0.9%1,.7%),在不同民族间汉族2%(1.7%,2.5%)及回族2%(0.1%,3.2%)较高,维吾尔族1%(0.3%,1.5%)随后。原发性高血压平均年龄为54.36岁,原发性醛固酮增多症平均年龄为45.20岁,两者间在年龄构成上P<0.001,具有统计学意义。结论原发性醛固酮增多症的检出率为2%,其患病年龄低于原发性高血压。
Objective To observe the prevalence of primary aldosteronism in hospitalized hypertensive patients in Xinjiang and to provide epidemiological support for the detection of secondary hypertension. Methods A total of 4 642 inpatients with hypertension in our hospital from 1997 to 2005 were selected, including 83 patients with primary aldosteronism. The diagnostic criteria were confirmed by surgery and pathology. 4095 patients with essential hypertension. In accordance with the guidelines for the diagnosis of hypertension in 1999 in China. Statistical methods using a 95% confidence interval (95% CI) and t test. Results The prevalence of essential hypertension was 88% (87.4%, 89.3%) in Xinjiang hypertensive population and the highest among Kazakhs was 92% (97.7%, 96.6%). The primary The prevalence of aldosteronism was 2% (1.4%, 2.2%), with 2% (1.7%, 2.9%) in men and 1% (0.9% 1, .7%) in females, % (1.7%, 2.5%) and Hui 2% (0.1%, 3.2%) were higher, followed by Uygur 1% (0.3%, 1.5%). The mean age of essential hypertension was 54.36 years. The mean age of primary aldosteronism was 45.20 years old. There was a significant difference between the two in age constitution (P <0.001). Conclusions The detection rate of primary aldosteronism is 2%, its age of onset is lower than that of essential hypertension.