在试管内显示奇效的许多药物用于人体时往往失效,原因是机体有阻止药物到达发挥最佳作用部位的屏障。日本熊本大学医学院的微生物学家前田广宣称,他研究出克服这种屏障的新方法。前田称他的方法为“特制蛋白法”(Proteintailoring),系由一组生物相容性聚合体组成一治疗作用的蛋白。用这种方式制备的药物治疗某些癌症已获得显著的成功。 Many drugs that show miraculous effects in vitro often fail when used in humans because the body has a barrier that prevents the drug from reaching its optimal site of action. Miyuki Maeda, a microbiologist at the Kumamoto University School of Medicine in Japan, said he has developed a new method to overcome this barrier. Maeda called his method “Protein tailoring,” a group of biocompatible polymers that make up a therapeutically active protein. Drugs prepared in this way have achieved significant success in the treatment of certain cancers.