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目的:探索中药藿香正气水肠道作用机制。方法:运用短路电流技术研究藿香正气水对结肠上皮细胞T84吸收分泌的影响。结果:藿香正气水在结肠上皮细胞T84的顶膜面上能激活一个由氯离子通道介导的分泌。结论:藿香正气水对肠道分泌的影响主要和氯离子通道有关。
Objective: To explore the mechanism of Chinese medicine Huoxiang Zhengqi water intestine. Methods: The effects of Huoxiangzhengqi water on the absorption and secretion of colonic epithelial cells T84 were studied by using short-circuit current technique. Results: Huoxiangzhengqi water can activate a chloride channel-mediated secretion on the apical membrane surface of colonic epithelial cells T84. Conclusion: The effect of Huoxiang Zhengqi on intestinal secretion is mainly related to chloride channel.