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目的了解医院多重耐药菌感染情况,建立干预措施,防控耐药菌在医院内传播。方法通过目标性监测和细菌检测方法,对住院患者标本进行检测和耐药菌分析。结果在2010年5-12月,从本医院住院病人标本中检出多重耐药菌225株,其中有141株分离自医院感染病人的标本,占62.7%。检出的多重耐药菌以革兰阴性杆菌为主,占检出总数的88%。院内感染多重耐药菌检出科室主要是呼吸内科、重症监护室和脑外科。结论该医院患者标本多重耐药菌检出率较高,其中多数来自医院感染患者标本,提示应加强临床抗菌药物应用管理。
Objective To understand the multi-drug resistant bacteria infection in hospital and establish interventions to prevent and control the spread of drug-resistant bacteria in the hospital. Methods By means of targeted monitoring and bacterial detection, the specimens of inpatients were tested and drug-resistant bacteria were analyzed. Results From May to December 2010, 225 multi-drug resistant strains were detected from inpatients in our hospital, of which 141 were isolated from patients with nosocomial infections, accounting for 62.7%. Gram-negative bacilli were the main multi-drug-resistant strains detected, accounting for 88% of the total number detected. Nosocomial infection with multi-drug-resistant bacteria detection department is mainly respiratory medicine, intensive care and brain surgery. Conclusions The detection rate of multidrug-resistant bacteria in the patients in this hospital is high, most of which come from the specimens of hospital-acquired patients, suggesting that the application of clinical antimicrobial agents should be strengthened.