糖尿病是重型地中海贫血(TM)患者铁超载的重要并发症之一。对1例TM患者在胰岛素基础上联合强化排铁治疗。随着铁蛋白的快速下降,患者胰岛素敏感性增加,胰岛素分泌功能改善,胰岛素用量逐步减少并最终停止使用。TM患者需监测其胰岛功能,强化排铁有望治愈早期发现的糖尿病。 Diabetes is one of the major complications of iron overload in patients with thalassemia major (TM). A case of TM patients on the basis of insulin to strengthen the iron treatment. With the rapid decline of ferritin, patients with increased insulin sensitivity, improved insulin secretion, insulin dosage gradually reduced and eventually stop using. Patients with TM need to monitor their islet function and intensify the iron discharge is expected to cure the early detection of diabetes.