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提高早产儿周围氧的浓度,可经皮肤吸收,而且早产儿愈小,上皮屏障愈弱,此种改变愈大。方法妊娠25~31周(平均27.6周)的早产儿13例,体重370~1380g,娩出后由于呼吸窘迫,均进行气管内插管、机械通气,吸入氧浓度(FiO_2)0.58~1.0(平均0.86)。其中3例有重症肺高压,给予妥拉苏林(1~2 mg/kg/hr)。患儿均于胸主动脉降部,留置氧电极,持续监测PaO_2,即将流经管道血液中PaO_2分度,从监测器上反馈于图表记录上使PaO_21mmHg,偏移2 mm,并测测PaO_2平均40.2mmHg,动脉血pH平均7.28。每例早产儿均裸体,水平仰卧于保育箱内,该箱容积20L,不密封,进入室
Improve the concentration of oxygen around the premature children, can be absorbed through the skin, and the smaller the preterm children, the weaker the epithelial barrier, the greater the change. Methods Thirteen preterm infants (370 to 1380g) with gestational age of 25 to 31 weeks (average 27.6 weeks) had endotracheal intubation and mechanical ventilation due to respiratory distress after delivery. The oxygen concentration (FiO_2) ranged from 0.58 to 1.0 (mean, 0.86 ). Three of the patients had severe pulmonary hypertension and received tolathulin (1-2 mg / kg / hr). Children were placed in the descending part of the thoracic aorta, leaving the oxygen electrode, continuous monitoring of PaO_2, about to flow through the blood PaO_2 indexing, from the monitor feedback on the chart record PaO_21mmHg, offset 2 mm, and measured PaO2 average 40.2mmHg, arterial pH average 7.28. Preterm infants were nude in each case, the level of supine in the incubator, the box volume 20L, unsealed, into the room