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目的:探讨结直肠癌患者术后C反应蛋白/血清白蛋白比值(CAR)对结直肠癌患者术后发生早期吻合口漏的预测价值。方法:对2016年9月至2019年9月期间就诊于本院胃肠外科的结直肠癌患者进行回顾性分析，包括患者的基线资料，术后第1、3、5、7天C反应蛋白(CRP)、降钙素原(PCT)和血清白蛋白(ALB)水平。根据术后7 d内是否有吻合口漏分为吻合口漏组和无吻合口漏组，并对两组相关数据进行统计分析。结果:吻合口漏组和无吻合口漏组患者的年龄、BMI、手术时间、术中出血量等基线数据差异均无统计学意义(n P>0.05)；但吻合口漏组的住院时间长于非吻合口漏组(n P<0.05)。吻合口漏组术后第3天CRP水平、第5天PCT水平均高于非吻合口漏组(n P<0.05)。吻合口漏组术后第3天和第5天的CAR值均高于非吻合口漏组(n P0.05), but the hospitalization time of the anastomotic leakage group was longer than that of the non anastomotic leakage group (n P<0.05). The CRP level on the 3rd and PCT level on the 5th day after operation in the anastomotic leakage group were higher than those in the non anastomotic leakage group, with significant difference (n P<0.05). The CAR value on the 3rd and 5th day after operation in the anastomotic leakage group was higher than those in the non anastomotic leakage group with significant difference (n P<0.05).n Conclusions:CAR can predict early anastomotic leakage in patients with colorectal cancer.