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肝炎引起的再生障碍性贫血(AA)预后较差,总病死率>85%,有学者提倡早期骨髓移植(BMT)。作者报告2例由非甲非乙型肝炎引起的一过性AA。例1为14岁男孩,因腹痛、恶心、呕吐及黄疸1周就诊。体查发现肝大,血清谷草转氨酶(SG0T)268IU/L,谷丙转氨酶(SGPT)619IU/L。2周后出现高热,渗出性咽炎,双侧颈淋巴结触痛。白细胞计数0.5×10~9/L,淋巴细胞占96%,单核细胞4%,血红蛋白7.5g/dl,血小板63×10~9/L,网织红细胞0.6%。两次作甲肝和乙肝血清学检查均为阴性。骨髓活检示有核细胞显著增生低下,病变符合AA特点。经静脉内应用抗生素、
Hepatitis-induced aplastic anemia (AA) has a poor prognosis, with a total case fatality rate of> 85%. Some scholars advocate early bone marrow transplantation (BMT). The authors report 2 patients with transient AA caused by non-A, non-B hepatitis. Example 1 A 14-year-old boy was referred for 1 week because of abdominal pain, nausea, vomiting and jaundice. Physical examination found that liver, serum aspartate aminotransferase (SG0T) 268IU / L, alanine aminotransferase (SGPT) 619IU / L. After 2 weeks of high fever, exudative pharyngitis, bilateral cervical lymph node tenderness. White blood cell count 0.5 × 10 ~ 9 / L, lymphocytes 96%, monocytes 4%, hemoglobin 7.5g / dl, platelets 63 × 10 ~ 9 / L, reticulocytes 0.6%. Two times for hepatitis A and hepatitis B serology were negative. Bone marrow biopsy showed significant proliferation of nucleated cells low, lesions consistent with AA characteristics. After intravenous antibiotics,