某些抗菌素的使用如氨苄青霉素、氯林可霉素、林可霉素、氯霉素以及先锋霉素等可以产生腹泻,程度轻者很短暂,且有自限性,严重者可表现为威胁生命的结肠炎,介乎这两者之间则为长时期的腹泻,即使停用有关抗菌素并给予对症治疗也无效。作者报道3例与抗菌素相关联的腹泻。例一因上呼吸道感染而接受氨苄青霉素治疗;例二则于手术前使用了新霉索,术后则应用了氯林可霉素、庆大霉素、先锋霉索Ⅰ及Ⅳ;例三则由于术后接受了氯林可霉素治疗。临床表现除腹泻外尚包括有腹部不适、便血、失血及低 The use of some antibiotics such as ampicillin, clindamycin, lincomycin, chloramphenicol and cephalosporins and other can produce diarrhea, the degree of light is very short and self-limiting, can be presented as a serious threat Colitis of life, between the two, is a long-term diarrhea that is ineffective even with the withdrawal of the antibiotic and symptomatic treatment. The authors reported 3 cases of diarrhea associated with antibiotics. In one case, ampicillin was given due to upper respiratory tract infection. In the second case, neomycin was used prior to surgery. Clinomycin, gentamicin and pioneer mycotoxins I and IV were applied after surgery. Due to postoperative clindamycin treatment. In addition to clinical manifestations of diarrhea, but also include abdominal discomfort, blood in the stool, blood loss and low