Epilepsy,one of the most frequent neurological afflictions in men characterized by excessive temporary neuronal discharges resulting in uncontrolled convuls
The neuromuscular blocking agents(NMBAs) are widely used in anesthesia as muscle relaxant.The steroid skeleton,decorated with two ammonium groups at proper
Recently,a series of piperidine linked aminopyrimidine derivatives are reported as H1V-1 NNRTIs with good potency in both enzyme and antiviral assays1-3In c
Ligustrazine(tetramethyl pyrazine,TMP,a major effective component of Chinese traditional herbal medicine Chuanxiong,has been reported to be a multifunctiona
A novel series of β-amino pyrrole-2-carbonitrile derivatives was designed and synthesized based on the three-dimensional binding modes of Denagliptin1 and