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患者男,45岁。右上臂结节3个月余,破溃、结痂1个月。皮损组织病理示:表皮角化过度,棘层显著肥厚,棘层内见较多大而透明的细胞团块;表皮嵴不规则延长、增宽处胞浆丰富,呈透明状,细胞间桥清晰可见,真皮浅层毛细血管扩张,血管周围见中性粒细胞为主的炎细胞浸润。PAS染色示透明细胞胞浆内有大量的糖原沉积。结合临床和组织病理特点诊断为透明细胞棘皮瘤。
Male patient, 45 years old. Right upper arm nodules more than 3 months, ulceration, scab 1 month. Histopathological examination showed that the epidermis was hyperkeratotic, the stratum spinosum was hypertrophic, and the stratum granulosum had many large and transparent cell masses. The epidermal ridges irregularly extended, the cytoplasm was widened and widened, and the intercellular bridges were clear Can be seen, superficial dermal capillaries dilated, see neutrophil-based inflammatory cell infiltration around the blood vessels. PAS staining revealed a significant amount of glycogen deposition in the cytoplasm of clear cells. Combined with clinical and histopathological diagnosis of clear cell acanthoma.