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目的 探讨术中植入125I粒子治疗腹腔恶性肿瘤的方法。方法 回顾性分析我院普外科2003年~2004年收治的术中植入125I粒子的110 例腹部恶性肿瘤病人的诊治经验。按肿瘤类型将病人分为胰腺癌组、胃癌组、结直肠组和肝癌组,随访6个月后对各组的术后近期疗效、术后并发症分别进行分析。结果 胰腺癌组局部控制率为85%,并发症发生率为20%;胃癌组分别为72%、25%;结直肠组为70%、39%;肝癌组为80%、27%。总的局部控制率达77%,并发症发生率为26%。结论 术中植入125I粒子治疗手术无法根治的腹腔恶性肿瘤疗效确切,是一种值得推广的治疗手段。
Objective To investigate the method of intraoperative implantation of 125I particles in the treatment of malignant tumors of the abdominal cavity. Methods A retrospective analysis of our hospital general surgery from 2003 to 2004 admitted intraoperative 125I seeds implantation in 110 cases of abdominal cancer diagnosis and treatment of patients. The patients were divided into pancreatic cancer group, gastric cancer group, colorectal cancer group and hepatocellular carcinoma group according to tumor type. After 6 months of follow-up, the short-term curative effect and postoperative complications of each group were analyzed respectively. Results The local control rate of pancreatic cancer was 85% and the incidence of complications was 20%. The percentage of gastric cancer was 72% and 25% respectively. The percentage of colorectal cancer was 70% and 39%. The percentage of liver cancer was 80% and 27% respectively. The total local control rate of 77%, the complication rate was 26%. Conclusion Intraoperative implantation of 125I particles in the treatment of intra-abdominal malignant tumors can not cure the exact effect, is a worthy of promotion of treatment.