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目的:探讨糖尿病周围神经病变患者采用银杏达莫联合α-硫辛酸治疗的临床疗效。方法:选取医院2014年10月—2015年10月收治的62例糖尿病周围神经病变患者,按数字表法分为对照组和观察组,每组31例患者。对照组患者仅用α-硫辛酸治疗,观察组患者则采用银杏达莫联合α-硫辛酸治疗。对比两组患者的治疗效果、治疗前后的疼痛程度及神经传导速度。结果:观察组腓总神经、正中神经的运动神经传导速度和感觉神经传导速度明显优于对照组,具有统计学意义(t=9.18、6.51、3.50、7.56,P均<0.05);观察组治疗后的VSA评分(1.76±0.65)分与对照组的(2.48±0.73)分相比明显较低,差异具有统计学意义(P<0.05);观察组患者治疗的临床总有效率(90.32%)和对照组的(67.74%)相比明显提高,差异具有统计学意义(P<0.05)。结论:糖尿病周围神经病变患者采用银杏达莫联合α-硫辛酸治疗的效果显著,不仅可有效缓解患者四肢麻木、疼痛等症状,促进血液循环、营养神经,从而改善患者的运动、感觉神经传导速度,加快患者康复。
Objective: To investigate the clinical efficacy of ginkgo-dipyridamole combined with α-lipoic acid in patients with diabetic peripheral neuropathy. Methods: Totally 62 patients with diabetic peripheral neuropathy admitted from October 2014 to October 2015 in our hospital were divided into control group and observation group according to the digital table method, with 31 patients in each group. Patients in the control group were treated with α-lipoic acid only, while patients in the observation group were treated with ginkgo-dipaloxazole combined with α-lipoic acid. The therapeutic effects of two groups of patients were compared, the degree of pain before and after treatment and nerve conduction velocity. Results: The motor nerve conduction velocity and sensory nerve conduction velocity of the common peroneal nerve and median nerve in the observation group were significantly better than those in the control group (t = 9.18, 6.51, 3.50, 7.56, P <0.05) The postoperative VSA score (1.76 ± 0.65) was significantly lower than that of the control group (2.48 ± 0.73), the difference was statistically significant (P0.05). The total clinical effective rate (90.32%) in the observation group was significantly lower than that in the control group Compared with the control group (67.74%), the difference was statistically significant (P <0.05). Conclusion: The treatment of diabetic peripheral neuropathy patients with gingko Damo combined with α-lipoic acid has significant effect, which not only can effectively relieve numbness and pain and other symptoms in patients with limbs, promote blood circulation and nourishing nerves, and thus improve the patient’s motor and sensory nerve conduction velocity , Speed up patient rehabilitation.