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目的 评价顺铂增敏放射治疗食管癌的疗效及并发症.方法 对30例中晚期食管癌进行顺铂(DDP)增敏的放射治疗并与同期的单纯放射治疗的食管癌30例进行疗效比较.DDP 20mg每周五次.放疗均用10Mev X线等中心治疗,剂量60 Gy～70 Gy/6～7 wk.结果 一、三、五年生存率分别为单纯放射组46.7%、20%、10%;放化疗组60%、30%、23%.结论 DDP增敏的放射治疗能提高食管癌的近期和远期疗效,且无严重的并发症.
Objective To evaluate the efficacy and complications of cisplatin sensitization in the treatment of esophageal cancer. Methods The efficacy of cisplatin (DDP) sensitization in 30 patients with advanced esophageal cancer was compared with that of 30 patients with esophageal cancer treated with radiotherapy alone. .DDP 20mg five times per week. The radiotherapy was treated with 10 MeV X-ray isocenter at doses of 60 Gy to 70 Gy/6 to 7 weeks. Results The one-, three-, and five-year survival rates were 46.7%, 20%, respectively in the radiotherapy group alone. 10%; radiotherapy and chemotherapy group 60%, 30%, 23%. Conclusion DDP sensitized radiotherapy can improve the short-term and long-term efficacy of esophageal cancer, and no serious complications.