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在放射性核素诊断中,用放射性核素标记红细胞进行循环血容量、红细胞贮存量测定和脾扫描所用的核素有~(197)Hg、~(51)Cr、~(111)In、~(99)Tc等。~(197)Hg用量大(6mg/人)真易引起中毒并发症,~(51)Cr半衰朋长,γ能量不适中,不宜于体外测定和不能重复进行观察。用~(99)Tc标记红细胞需用锡制剂(高达2mg),因而应用受到限制。而无载体~(203)Pb,其γ能量适中,半衰期短,在制剂中不含有毒性物质,可进行重复观察。
In radionuclide diagnostics, radionuclide-labeled erythrocytes were used for determination of circulating blood volume, erythrocyte storage, and splenic scintigraphy with ~ (197) Hg, ~ (51) Cr, ~ (111) In, 99) Tc and so on. ~ (197) Hg dosage (6mg / person) can easily lead to poisoning complications, ~ (51) Cr half-turn long, γ energy discomfort, not in vitro determination and can not be repeated. The use of ~ (99) Tc labeling of red blood cells with tin preparations (up to 2mg), and thus the application is limited. Without carrier ~ (203) Pb, γ energy moderate, short half-life, in the preparation does not contain toxic substances, can be repeated observation.