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目的 观察依济复在预防及治疗放射性皮炎和粘膜炎中的作用。方法 1999年 10月～ 2 0 0 0年 9月 ,应用依济复喷剂预防及治疗 5 0例行放射治疗患者 (预防治疗组 ) ,并设同等数量常规处理的患者为对照组。结果 预防治疗组Ⅱ度以上放射性皮炎发生率为 2 0 %,对照组 93.3%,两组有显著性差异 (P <0 .0 0 5 ) ;预防治疗组Ⅱ度以上放射性粘膜炎发生率为 10 %,对照组为 90 %,两组也具有显著性差异 (P <0 .0 0 5 )。结论 依济复对Ⅱ度以上放射性皮炎和粘膜炎的预防有一定作用 ,对放射性皮炎和粘膜炎的治疗效果显著 ,可以将放射性皮炎和粘膜炎基本控制在Ⅱ度以内 ,起到止痛、止痒、促进伤口愈合等作用。
Objective To observe the effect of Yi J Fu on the prevention and treatment of radiation dermatitis and mucositis. Methods From October 1999 to September 2000, Yizhi Fu Spray was used to prevent and treat 50 cases of patients with radiotherapy (prophylaxis and treatment group), and the same number of routine treatment patients as the control group. Results The incidence of radiodermatitis in grade Ⅱ and above was 20% in control group and 93.3% in control group, with significant difference between the two groups (P <0.05). The incidence of radiopharmaceutical mucositis above grade Ⅱ in prevention group was 10 %, Control group was 90%, two groups also had significant difference (P <0.05). Conclusion Yi-Fu Fu on the second degree of radiation dermatitis and mucositis prevention play a role in the treatment of radiation dermatitis and mucositis significant effect of radiodermatitis and mucositis can be basically controlled within Ⅱ degrees, play a pain, itching , Promote wound healing and other effects.