1病例介绍患者女,44岁,以“部分关节发作性红肿热痛20余年”于2012年8月6日入院。20余年前无明显诱因右足第一跖趾关节突发剧烈疼痛、肿胀,伴局部皮肤发红、发热,服用不详止痛药治疗,有效。后多年来时有发作,发作时疼痛剧烈,不能行走,服用止痛药缓解,逐渐上述关节处出现多个皮下结节,随病情进 1 Case Description Female patient, 44 years old, with “part of the joint painful swelling and pain more than 20 years ” on August 6, 2012 admission. More than 20 years ago, no obvious incentive for the first right foot metatarsophalangeal joint severe pain, swelling, with local skin redness, fever, taking unknown painkillers, effective. Occurred after many years, the onset of severe pain, can not walk, take painkillers to ease, and gradually above the joints appear multiple subcutaneous nodules, with the disease into