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患者男性,37岁,工人。因头晕,乏力,活动后心悸气短6个月。经外院骨穿诊断为骨髓增生异常综合征(RAEB-T),用Ara-C20mg/日连用4周,因停药后外周血幼稚细胞比例持续性升高,于1992年9月27日入院.重度贫血外貌,胸骨压痛(+),心肺(-),肝脾不大.Hb45g/L,WBC10.2×10~9/L,中性粒细胞0.05,淋巴细胞0.1,幼稚细胞0.85,血小板3.8×10~9/L.骨髓形态学及细胞化学符合急性粒细胞性白血病 AML(M_2)。用 COAP 方案(长春新碱1.5mg/日×1,环磷酰胺200mg/日×5,Ara-C100mg/日×5,强地松30mg/日×5),1疗程后 WBC3.2×10~9/L,中性粒细胞0.1,患者右下腹饱满,轻度压痛,
Male patient, 37 years old, worker. Due to dizziness, fatigue, activity shortness of breath after 6 months. It was diagnosed as myelodysplastic syndrome (RAEB-T) by the bone marrow of the outer hospital and was treated with Ara-C 20mg / day for 4 weeks. The patient was admitted to hospital on September 27, 1992 due to the persistent increase in the proportion of naive cells in the peripheral blood after stopping the treatment. Hb45g / L, WBC10.2 × 10 ~ 9 / L, neutrophils 0.05, lymphocytes 0.1, naive cells 0.85, platelets 3.8 × 10 ~ 9 / L. Bone marrow morphology and cytochemistry in line with acute myeloid leukemia AML (M_2). The COAP regimen (vincristine 1.5mg / day × 1, cyclophosphamide 200mg / day × 5, Ara-C100mg / day × 5, prednisone 30mg / day × 5), after a course of treatment WBC3.2 × 10 ~ 9 / L, neutrophils 0.1, patients with right lower quadrant full, mild tenderness,