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目的:观察中西医结合治疗复发性口腔溃疡的临床疗效。方法:120例复发性口腔溃疡随机分为2组各60例,对照组采用甲硝唑、左旋咪唑等西药治疗;中西医结合组在对照组治疗基础上加用中药方治疗。比较2组患者近期疗效、远期疗效及口腔健康影响程度量表调查(OHIP-14)评分。结果:近期痊愈率中西医结合组66.67%,对照组40.00%,2组比较,差异有显著性意义(P<0.05);总有效率2组比较,差异无显著性意义(P>0.05)。远期总有效率中西医结合组90.00%,对照组75.00%,2组比较,差异有显著性意义(P<0.05)。治疗后1年对2组随访调查,结果中西医结合组OHIP-14量表的功能限制、生理性疼痛、生理障碍及总分均低于对照组(P<0.05)。结论:中西医结合治疗复发性口腔溃疡临床疗效显著,同时改善患者的生活质量。
Objective: To observe the clinical efficacy of integrated traditional Chinese and western medicine in the treatment of recurrent oral ulcer. Methods: 120 cases of recurrent oral ulcer were randomly divided into two groups of 60 cases, the control group with metronidazole, levamisole and other western medicine treatment; Integrative Medicine group in the control group based on the treatment with Chinese medicine. Short-term efficacy, long-term efficacy and oral health impact scale survey (OHIP-14) scores were compared between the two groups. Results: The cure rate was 66.67% in Integrative Medicine Group and 40.00% in Control Group. There was significant difference between the two groups (P <0.05). There was no significant difference in total effective rate between the two groups (P> 0.05). Total effective long-term combination of traditional Chinese and Western medicine group 90.00%, 75.00% in the control group, the two groups, the difference was significant (P <0.05). One year after treatment, follow-up survey was conducted in two groups. Results The functional limit, physiological pain, physical disturbance and total score of OHIP-14 in Integrative Medicine group were lower than those in control group (P <0.05). Conclusion: Integrative Chinese medicine treatment of recurrent oral ulcer clinical efficacy significantly, while improving the quality of life of patients.