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目的探讨C反应蛋白(CRP)和腺苷脱氨酶(ADA)在老年性胸腔积液鉴别诊断中的价值。方法对112例老年性胸腔积液患者(其中结核性42例,癌性36例,炎性34例)的临床资料进行回顾性分析,并对各组的CRP和ADA水平进行比较。结果结核性胸腔积液CRP水平明显高于癌性胸腔积液,差异有统计学意义[(38.9±14.3)mg/Lvs(8.9±2.1)mg/L,P<0.01],而与炎性组差别无统计学意义[(38.9±14.3)mg/Lvs(34.7±12.7)mg/L,P>0.05];结核性胸腔积液ADA水平明显高于癌性胸腔积液与炎性胸腔积液,差异有统计学意义[(31.2±12.1)U/Lvs(14.1+8.2)U/L、(13.9±5.3)U/L,P<0.01]。结论联合检测CRP和ADA对老年结核性和癌性胸腔积液具有鉴别诊断价值。
Objective To investigate the value of C-reactive protein (CRP) and adenosine deaminase (ADA) in the differential diagnosis of senile pleural effusion. Methods The clinical data of 112 elderly patients with pleural effusion (including 42 tuberculosis, 36 cancerous and 34 inflammatory) were retrospectively analyzed, and the levels of CRP and ADA in each group were compared. Results The level of CRP in tuberculous pleural effusion was significantly higher than that in cancerous pleural effusion ([(38.9 ± 14.3) mg / L vs (8.9 ± 2.1) mg / L, P <0.01] (38.9 ± 14.3 mg / L vs 34.7 ± 12.7 mg / L, P> 0.05). ADA in tuberculous pleural effusion was significantly higher than that in cancerous pleural effusion and inflammatory pleural effusion, The difference was statistically significant [(31.2 ± 12.1) U / Lvs (14.1 + 8.2) U / L, (13.9 ± 5.3) U / L, P <0.01]. Conclusions Combined detection of CRP and ADA has differential diagnostic value in senile tuberculous and cancerous pleural effusions.