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目的通过湖北省随州市办理健康证的从业人员抗百日咳毒素IgG(PT-IgG)血清特异性抗体水平检测,了解该人群百日咳感染率。方法采集办理健康证的508名17-63岁从业人员血清标本,采用酶联免疫吸附试验(ELISA)检测血清抗PT-IgG抗体,采用描述性方法对数据进行分析。结果在508名调查对象中,抗PT-IgG抗体阳性18名,阳性率为3.54%,几何平均浓度(GMC)为4.67IU/ml。以27-36岁人群易感性最高,抗体阳性率为4.40%,GMC为3.59IU/ml。各年龄组之间、地区之间及性别之间抗体阳性率无显著性差异;几何平均浓度(GMC)在地区之间及性别之间无显著性差异,但在各年龄组之间有显著性差异。结论 2016年湖北省随州市办理健康证的从业人员百日咳感染率高,应该引起重视,防止百日咳的传播流行。
Objective To detect the level of pertussis toxin IgG (PT-IgG) serum-specific antibody in health certificate practitioners in Suizhou City, Hubei Province, and to understand the prevalence of pertussis in this population. Methods A total of 508 serum samples from 17-to-63-year-old practitioners who took health certificates were collected. Serum anti-PT-IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA) and descriptive data were analyzed. Results Of the 508 respondents, 18 were positive for anti-PT-IgG antibody with a positive rate of 3.54% and a geometric mean concentration (GMC) of 4.67 IU / ml. The highest susceptibility to 27-36-year-old population, the antibody positive rate was 4.40%, GMC was 3.59IU / ml. There was no significant difference in antibody positive rate among different age groups, between regions and between sexes. There was no significant difference in GMC among regions and between sexes, but there was significant difference among all age groups difference. Conclusion The prevalence of whooping cough in practitioners applying for health certificate in Suizhou in 2016 is high and should be taken seriously to prevent the spread of pertussis.