蕈样肉芽肿(MF)是一种皮肤淋巴增生性疾病。随着病情的发展,皮肤以外的组织亦可受累。为了证实是否有骨髓受累,作者对19例MF病人进行了骨髓针吸活检。本研究中19例MF病人,均经组织学证实。男11例、女8例;年龄为31～85岁(平均64岁);病情2月～55年不等;均为2、3、4期患者。其中1例Sézary综合征的病人分类为3期,2例暴发性MF病人分别分类为3期和4期。以上病例根据Radner针吸技术的方法在髂后上脊进行骨髓活检,骨髓和骨髓吸出物进行了连续切片和用苏木素-伊红染色。骨髓印片和周围血涂片用May-Gr(?)wald-Giemsa染色。结果19例病人中仅2例具有病理骨髓所见,其 Mycosis fungoides (MF) is a cutaneous lymphoproliferative disorder. As the condition progresses, tissues other than the skin can also be involved. To confirm whether there was bone marrow involvement, the author performed a needle biopsy in 19 patients with MF. In this study, 19 cases of MF patients were confirmed by histology. 11 males and 8 females; aged 31-85 years (average 64 years); disease ranging from 2 months to 55 years; are 2,3,4 patients. One case of Sézary syndrome was classified as stage 3, and 2 cases of fulminant MF were classified as stage 3 and stage 4, respectively. In the above cases, bone marrow biopsies were performed on the posterior tibial superior ridge according to the method of Radner needle suction technique. Bone marrow and bone marrow aspirate were serially sectioned and stained with hematoxylin-eosin. Bone marrow prints and peripheral blood smears were stained with May-Gr (?) wald-Giemsa. Results Only 2 of the 19 patients had pathological bone marrow findings.