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对４９ 例肠易激综合征（ＩＢＳ） 患者和１０ 例对照者进行乳果糖呼氢试验（ＬＨＢＴ） ，测定口回盲瓣通过时间及小肠细菌过度生长的阳性率，对ＬＨＢＴ 阳性者用西沙必利治疗７ ｄ 并进行比较。结果：ＩＢＳ腹泻型及便秘型患者的口回盲瓣通过时间均较对照组明显延长（ Ｐ＜ ０ ．０５） ，２ 型间小肠细菌过度生长的阳性率无差别（ Ｐ＞ ０ ．０５） ，２ 型治疗后口回盲瓣通过时间明显改善（ Ｐ＜ ０ ．０５） ，临床症状好转。提示：小肠动力紊乱可导致小肠细菌过度生长，并可能是肠易激综合征的发病因素之一，ＬＨＢＴ 可为ＩＢＳ的病因探索和治疗提供依据。
49 patients with irritable bowel syndrome (IBS) patients and 10 controls were lactulose hydrogen test (LHBT), oral ileocecal valve clearance time and the positive rate of intestinal bacterial overgrowth, LHBT positive with Xisha Palliative treatment for 7 days and comparison. Results: The passage time of oral ileocecal valve in patients with IBS diarrhea and constipation was significantly longer than that in control group (P <0.05). There was no significant difference in the positive rate of intestinal bacterial overgrowth between two groups (P> 0.05) , Type 2 after oral ileocecal valve clearance time was significantly improved (P <0 .05), clinical symptoms improved. Tip: Intestinal motility disorders can lead to intestinal bacterial overgrowth, and may be one of the pathogenesis of irritable bowel syndrome, LHBT can provide the basis for the exploration and treatment of IBS.