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用放射免疫法和ELISA法联合检测68例胃病患者胃液、血清中癌胚抗原(CEA)、β2-微球蛋白(β2-MG)和幽门螺杆菌抗体(Hp-Ab)含量。结果表明:①胃癌组胃液CEA和β2-MG浓度明显升高,与正常对照组比较有显著差异(P<0.01)。②良性病变组血清Hp抗体阳性率高于胃癌组(P<0.05)。提示联合检测胃液CEA、β2-MG和血清Hp抗体对胃癌诊断有一定临床价值。
The contents of carcinoembryonic antigen (CEA), β2-microglobulin (β2-MG) and Helicobacter pylori antibody (Hp-Ab) in gastric juice and serum of 68 patients with gastric diseases were detected by radioimmunoassay and ELISA. The results showed that: 1 The concentrations of CEA and β2-MG in the gastric juice of gastric cancer group were significantly higher than those in the normal control group (P<0.01). The positive rate of serum Hp antibody in benign lesions was higher than that in gastric carcinoma (P<0.05). It is suggested that the combined detection of gastric juice CEA, β2-MG and serum Hp antibody has a certain clinical value in the diagnosis of gastric cancer.