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采用免疫组化染色方法检测４０例前列腺癌（Ｐｅａ）、２２例前列腺增生症（ＢＰＨ）及１４例正常前列腺（ＮＰ）组织中Ｆａｓ、ＦａｓＬ、Ｂｃｌ－２及Ｂａｘ的表达。结果表明：①Ｆａｓ、ＦａｓＬ、Ｂａｘ表达于所有被检测的组织中；Ｂｃｌ－２表达于７５．０％Ｐｃａ组织、５４．５％ＢＰＨ组织、３５．７％ＮＰ组织。Ｆａｓ在Ｐｅａ中表达强度最弱（Ｐ＜０．０５）。Ｐｅａ与ＢＰＨ及 ＮＰ组织比较，Ｂｃｌ－２表达差异有显著性意义（Ｐ＜０． ０５）。②在 Ｐｅａ组织中，Ｂａｘ表达与 Ｆａｓ、ＦａｓＬ及 Ｂｃｌ－２表达均呈正相关，ＦａｓＬ表达与Ｂｃｌ－２表达呈正相关（Ｐ＜０．０５）。③Ｂａｘ在高级别Ｐｃａ中的表达明显强于在低级别中的表达（Ｐ＜０．０５）。
Immunohistochemical staining was used to detect the expressions of Fas, FasL, Bcl-2 and Bax in 40 cases of prostate cancer (Pea), 22 cases of benign prostatic hyperplasia (BPH) and 14 cases of normal prostatic (NP) tissues. The results showed that: (1) Fas, FasL and Bax were expressed in all tested tissues; Bcl-2 was expressed in 75.0% Pca, 54.5% BPH and 35.7% NP tissues. Fas expression was the weakest in Pea (P <0.05). Pea and BPH and NP organizations, Bcl-2 expression was significantly different (P <0. 05). ② In Pea tissue, the expression of Bax was positively correlated with the expression of Fas, FasL and Bcl-2, while the expression of FasL was positively correlated with the expression of Bcl-2 (P <0.05). ③Bax expression in high-grade Pca was significantly higher than in low-grade expression (P <0.05).