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目的:通过分析子宫乳头状浆液性癌的临床病理特点,提出两种截然不同的子宫内膜癌的区别所在。方法:自1982年5月1日至1994年4月30日,共收治子宫内膜癌110例,对其进行回顾性研究,并对其结果行统计学处理。结果:子宫乳头状浆液性癌10例(占9.1%)。本病与普通子宫内膜癌的发病相关因素如高血压、糖尿病、肥胖、长期持续雌激素刺激等无关,且本病有较明显的淋巴转移倾向(50%),分化明显不良(组织学分级3级占50%),80%的病例肌层浸润深度超过1/2肌层(P<0.01),有明显的宫外转移倾向(P<0.01),且术前分期不够准确。结论:本病在临床与病理学特点和普通子宫内膜癌截然不同,并且需要手术探查予以准确分期。
Objective: To analyze the clinicopathological features of uterine papillary serous carcinoma and to propose the difference between two distinct types of endometrial carcinoma. Methods: From May 1, 1982 to April 30, 1994, a total of 110 cases of endometrial cancer were treated and retrospectively studied. The results were statistically analyzed. Results: Uterine papillary serous carcinoma in 10 cases (9.1%). The disease and the incidence of endometrial cancer-related factors such as hypertension, diabetes, obesity, long-term continuous estrogen stimulation has nothing to do, and the disease has a more obvious tendency of lymphatic metastasis (50%), poorly differentiated (histological grade 3 grade accounted for 50%), 80% of the cases of myometrial invasion depth of more than 1/2 muscle (P <0.01), there is a clear tendency of extrauterine metastasis (P <0.01), and preoperative staging is not accurate enough . Conclusion: The disease in the clinical and pathological features and general endometrial cancer are completely different, and the need for surgical exploration to be accurately staging.