论文部分内容阅读
目的探究小儿先天性肾积水患儿血清Cys C、β2-MG、α1-MG含量的临床意义。方法选取先天性肾积水患儿48例作为观察组,另选取同期健康体检小儿48例作为对照组。记录观察组术前和术后血清中Cys C、β2-MG、α1-MG的含量水平,并将治疗前后血清Cys C、β2-MG、α1-MG含量和对照组进行比较。结果治疗前后患儿血清Cys C、β2-MG、α1-MG含量低于治疗前(P<0.05)。观察组治疗前各项指标与对照组比较差异有统计学意义(P<0.05);观察组治疗后各项指标与对照组比较差异无统计学意义(P>0.05)。结论血清Cys C、β2-MG、α1-MG含量可作为评价小儿先天性肾积水患儿在治疗后肾功能改善的重要指标,同时也可以作为患儿在术前对病情的正确定位手段。
Objective To investigate the clinical significance of serum Cys C, β2-MG and α1-MG in children with congenital hydronephrosis. Methods 48 cases of children with congenital hydronephrosis as the observation group, the other 48 cases of the same period healthy children were selected as the control group. The levels of Cys C, β2-MG and α1-MG in the observation group before and after surgery were recorded, and the contents of Cys C, β2-MG and α1-MG before and after treatment were compared with those in the control group. Results Serum levels of Cys C, β2-MG and α1-MG in children before and after treatment were lower than those before treatment (P <0.05). There were significant differences between the observation group before treatment and the control group (P <0.05). There was no significant difference between the observation group and the control group after treatment (P> 0.05). Conclusions Serum levels of Cys C, β2-MG and α1-MG can be used as an important index to evaluate the improvement of renal function in infants with congenital hydronephrosis. It can also be used as a correct method of positioning the disease in children before operation.