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端粒是真核染色体末端的特殊结构，人端粒由６个碱基重复序列（ＴＴＡＧＧＧ）和结合蛋白组成［１］。端粒有重要的生物学功能，能够稳定染色体，防止其末端融合；保护染色体结构基因；调节正常细胞生长［２］。正常细胞在进行ＤＮＡ复制时，５’端出现８～１２对的碱基缺失，
Telomeres are a special structure at the end of eukaryotic chromosomes. Human telomeres consist of a 6-base repeat (TTAGGG) and a binding protein [1]. Telomeres have important biological functions that stabilize chromosomes and prevent their terminal fusion; protect the chromosomal structural genes; and regulate normal cell growth [2]. Normal cells in the DNA replication, the 5 ’end 8 to 12 pairs of base deletions,