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2378例16～35岁健康妇女(共12250个周期)使用含Gestodene(δ-5-LNG)75μg+EE30μg的口服避孕药(OC)。这些妇女从未使用或停服OC半年以上。已知或怀疑妊娠、哺乳、产后月经尚未恢复、患慢性疾病、血管病变、子宫发育异常、正在使用甾体或其他药物的妇女均不作研究对象。每周期服药21天,停药7天。服药当时、服药后3、6个月时各随访1次。结果中途停用共440例(18.5％),其中由于药物原因(怀孕、不
2378 healthy women aged 16-35 years (12250 cycles total) received an oral contraceptive (OC) containing Gestodene (δ-5-LNG) 75 μg + EE 30 μg. These women have never used or stopped OC for more than six months. Known or suspected pregnancy, breastfeeding, postpartum menstruation has not yet recovered, suffering from chronic diseases, vascular disease, uterine dysplasia, are in the use of steroids or other drugs in women are not subject. Take 21 days per cycle, withdrawal for 7 days. At the time of medication, 3,6 months after taking each visit 1 time. Results A total of 440 patients (18.5%) discontinued halfway, which due to drug causes (pregnancy, no