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目的探讨不同水平的高碘摄入对儿童智力发育水平的影响。方法以8~10岁学生为研究对象,按居住地水碘含量分为NI、IE300,500和1000等4组,水碘含量中位数分别为19.70,367.90,655.95和1440.45μg/L,NI为对照组。测试中国联合型瑞文测验,B超检查甲状腺。结果IE300,500,1000各组学生智商(IQ)分别为100.22,100.45和97.56分,与NI组(99.55)比较,差异无统计学意义(P>0.05)。智力低下发生率NI、IE300,500,1000各组分别为1.86%,1.92%,2.99%和0,差异无统计学意义(P>0.05)。NI、IE300,500,1000组B超甲肿率在0~2.94%之间。Logistic回归分析表明,智力低下主要原因与母亲文化水平有关。结论在水碘300~1500μg/L之间的碘过多环境中生活的学生智力发展正常,高碘不是智力低下的危险因素。
Objective To explore the effect of different levels of high iodine intake on children’s mental development. Methods The subjects aged from 8 to 10 years were divided into 4 groups: NI, IE300, 500 and 1000 according to the concentration of iodine in their place of residence. The median iodine concentration in water was 19.70, 367.90, 655.95 and 1440.45 μg / L, respectively. NI For the control group. Test the Chinese joint Ruvin test, B-check the thyroid. Results The IQ of students in each group was 100.22, 100.45 and 97.56, respectively. There was no significant difference between the two groups (P> 0.05). The prevalence of mental retardation in NI, IE300, 500 and 1000 groups was 1.86%, 1.92%, 2.99% and 0 respectively, with no significant difference (P> 0.05). NI, IE300, 500,1000 group B over-grafting rate between 0 ~ 2.94%. Logistic regression analysis showed that the main reason of mental retardation was related to the level of mother’s education. Conclusions Students living in iodine environment with 300 ~ 1500 μg / L of water iodine have normal intelligence development. High iodine is not a risk factor for mental retardation.