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目的:评价抗菌新药司帕沙星片剂的临床疗效及安全性.方法:以洛美沙星片剂为对照,在73例急性细菌性感染患者中进行随机对照性研究.结果:试验组的痊愈率(84.21%)、有效率(92.11%)均高于对照组的痊愈率(65.71%)和有效率(82.86%),但统计学差异无显著性(P＞0.05).试验组患者不良反应发生率(5.3%)显著低于对照组(14.3%),P＜0.05.结论:在细菌感染性疾病的治疗中,司帕沙星片剂优于洛美沙星片剂.“,”Aim: to evaluate the clinical efficacy and safety of Sparfloxacin tablets, a random con-trast study compared with Lomefloxacin tablts in 73 patients with acute infections caused by bacteria wasperformed. Result: the recovered rate (84. 21 % ) and effective rate (92. 11 % ) in the test group werehigher than the recovered rate (65. 71 % ) and effective rate (82. 86% ) in the contrast group, thoughthere were no significant differance statistically (P >O. O5). The side - effetive rate was 5. 3% in thetest group, which was lower than that (14. 3% ) in control group (P < 0. 05 ). Conclusion:Sparfloxacin tablets are better than Lomefloxacin tablets in treating acute infectious-diseases caused by bac-teria.