论文部分内容阅读
目的 探讨窒息对早产儿肾功能的影响。方法 对41例早产并低出生体重儿(观察组23例,对照组18例)的排尿时间、尿量、尿液分析、血尿素氮、血肌酐和电解质水平进行回顾性分析,并对胎龄与血肌酐相关性进行探讨。结果 41例患儿排尿均无延迟,尿液分析均无异常,观察组3例少尿。血尿素氮≥7. 50mmol/L观察组9例,平均(10. 58±2. 54)mmol/L;对照组3例,平均(7. 57±1. 56)mmol/L,两组比较差异有统计学意义(P<0. 05)。两组共检测血肌酐37例,血肌酐≥88. 0μmol/L观察组11例( 11 /21 ),占52. 4%,平均(110. 8±25. 3)μmol/L;对照组3例(3 /16),占18. 7%,平均(110. 7±4. 7)μmol/L;观察组血肌酐增高发生率显著高于对照组(P<0. 01)。血肌酐升高与胎龄无明显相关性。结论 早产儿窒息后肾损害发生率很高,加强围生期保健,预防早产和窒息,及时处理胎儿宫内窘迫,新生儿窒息给予正确复苏是降低其发生率的有效措施。
Objective To investigate the effect of asphyxia on renal function in premature infants. Methods The urinary time, urine output, urinalysis, blood urea nitrogen, serum creatinine and electrolytes in 41 preterm and low birth weight infants (23 in observation group and 18 in control group) were retrospectively analyzed. The gestational age Correlation with serum creatinine to explore. Results There was no delay in urination in 41 cases, no abnormalities in urinalysis, and oliguria in 3 cases in observation group. The blood urea nitrogen≥7. 50mmol / L observation group, 9 cases, mean (10. 58 ± 2. 54) mmol / L; control group, 3 patients (average 57.56 mmol / L) The difference was statistically significant (P <0.05). 37 cases of serum creatinine were detected in two groups, blood creatinine ≥88. 0μmol / L in the observation group, 11 cases (11/21), accounting for 52. 4%, an average of (110.8 ± 25.3 μmol / L; control group 3 (3/16), accounting for 18.7%, with an average (110.7 ± 4.7 μmol / L). The incidence of serum creatinine in the observation group was significantly higher than that in the control group (P <0.01). No significant correlation between serum creatinine and gestational age. Conclusions The incidence of renal damage after asphyxia in preterm infants is very high. It is an effective measure to reduce perinatal health, prevent premature birth and asphyxia, manage fetal distress in time, and correct resuscitation of asphyxiated neonates.