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目的探讨天台乌药散对晚期癌症患者疼痛缓解的临床疗效观察。方法将60例符合入选标准的晚期癌症患者随机分为两组各30例。对照组予抗感染、支持、止痛等常规西医治疗,治疗组在对照组治疗基础上予以天台乌药散基础方药随症加减治疗,两组均连续治疗4 W。观察治疗前后患者生活质量QOL评分、卡氏评分、疼痛强度分级等各项指标的改变情况。结果治疗组患者生活质量QOL评分、卡氏评分、体重较对照组有明显改善,差异有统计学意义(P<0.05);治疗组患者因服用止疼药产生的主要不良反应便秘,恶心呕吐,头昏嗜睡较观察组有明显减少,两组差异有统计学意义(P<0.05)。结论天台乌药散能提高晚期癌症患者的生活质量,能有效控制癌痛,且可明显减轻口服止痛药引起的便秘,恶心呕吐,头昏嗜睡等不良反应。是晚期癌症疼痛患者缓解疼痛改善生活质量的有效治疗方法。
Objective To investigate the clinical effect of roof wuyusan on patients with advanced cancer pain relief. Methods Sixty patients with advanced cancer who meet the inclusion criteria were randomly divided into two groups of 30 patients. The control group was given anti-infection, support, analgesic and other conventional Western medicine treatment group in the control group based on the treatment to be Tiantai Wuxian scattered basic prescriptions with the disease plus treatment, both groups were treated 4 W. Before and after treatment, the quality of life QOL score, Karnofstal score, pain intensity grading and other indicators of change. Results The quality of life QOL score, Karnofsky score and body weight in the treatment group were significantly improved compared with the control group (P <0.05). The main side effects of the treatment group were constipation, nausea and vomiting, Dizziness and drowsiness than the observation group was significantly reduced, the difference between the two groups was statistically significant (P <0.05). Conclusion Tiantai Wuliu Powder can improve the quality of life of patients with advanced cancer, can effectively control cancer pain, and can significantly reduce the oral painkillers caused by constipation, nausea and vomiting, drowsiness and lethargy and other adverse reactions. It is an effective treatment for patients with advanced cancer pain to relieve pain and improve the quality of life.