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目的探讨软骨母细胞瘤(chondroblastoma,CB)的MRI表现特点及其病理基础。资料与方法分析经手术病理证实的13例CB的MRI表现特征,并与病理切片进行对照研究。结果全部病例在T1WI、T2WI上呈混杂信号。7例病灶边缘在T1WI及T2WI上均可见低信号环。9例有病灶邻近软组织肿胀和(或)关节囊肿胀。8例病灶周围骨髓腔内见水肿带。12例增强扫描均有不均匀明显强化。病理镜下主要由软骨母细胞和大小不等的多核巨细胞组成;7例肿瘤细胞间可见致密粗颗粒状钙盐沉积。6例可见含有暗红色液体囊腔,以及含铁血黄素沉着和组织凝固坏死。结论 CB的MRI表现较具特征性,MRI能反映其病理特性,是诊断CB的重要影像学方法 。
Objective To investigate the MRI features and pathology of chondroblastoma (CB). Materials and Methods MRI features of 13 cases of CB confirmed by surgery and pathology were analyzed and compared with pathological sections. Results All cases presented mixed signals on T1WI and T2WI. Seven cases of lesion edge in T1WI and T2WI are seen low signal ring. Nine patients had lesions adjacent to soft tissue swelling and / or joint capsule swelling. 8 cases of bone marrow cavity around the cavity with edema zone. 12 cases of enhanced scanning were significantly enhanced uneven. Pathological microscopic mainly by the chondroblasts and the size of the multinucleated giant cells; 7 dense tumor cells between the coarse granular calcium deposition. 6 cases showed dark red liquid cysts, and hemosiderin deposition and tissue coagulation necrosis. Conclusion The MRI findings of CB are more characteristic. MRI can reflect the pathological features of CB. It is an important imaging method for the diagnosis of CB.