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目的:分析二甲胍和胰岛素治疗老年社区糖尿病的临床治疗效果。方法:选取2014年8月至2015年12月期间某社区治疗2型糖尿病的87例老年患者作为研究对象,根据抽取的方式将其分为对照组(n=41)和观察组(n=46),对照组患者行常规胰岛素治疗,观察组行二甲胍治疗,对比两组患者的临床疗效。结果:治疗前,两组患者的空腹血糖、餐后2h血糖以及糖化血红蛋白等相关指标水平比较(P>0.05),治疗后,观察组患者的空腹血糖、餐后2h血糖以及糖化血红蛋白等相关水平改善不优于对照组(P<0.05),对照组患者不良反应发生率为4.9%,观察组患者不良反应发生率为6.5%,两组患者的不良反应发生率比较(x~2=0.108,P>0.05)。结论:二甲双胍和胰岛素治疗老年社区糖尿病,均能有效的改善了患者的临床指标水平,不良反应少,安全有效,均是临床值得推广应用的治疗方法。
Objective: To analyze the clinical effect of metformin and insulin in the treatment of elderly community diabetes mellitus. Methods: A total of 87 elderly patients with type 2 diabetes in a community from August 2014 to December 2015 were selected as study subjects and divided into control group (n = 41) and observation group (n = 46) ). The patients in the control group underwent routine insulin therapy. The observation group was treated with dimethylguanidine, and the clinical efficacy was compared between the two groups. Results: Before treatment, fasting blood glucose, postprandial 2h blood glucose and glycosylated hemoglobin and other related indicators were compared (P> 0.05). After treatment, the fasting blood glucose, postprandial blood glucose and hemoglobin A1c (P <0.05), the incidence of adverse reactions in the control group was 4.9%, the incidence of adverse reactions in the observation group was 6.5%, and the incidence of adverse reactions in both groups was significantly higher than that in the control group (x 2 = 0.108, P> 0.05). Conclusion: Both metformin and insulin can improve the level of clinical indicators in patients with community-based diabetes mellitus effectively, with few adverse reactions and safe and effective treatment. All these are worthy of clinical application.