食管粘膜上皮癌变的发生与发展和一切事物一样,是一个不断地由量变到质变、质量互变的运动过程。量变是指处于相对平衡时的运动状态。当实验动物食管粘膜上皮接触致癌物的初期,表现为稳定、无反应外观,实际上正开始着量变运动。尽管既不能从症状体征上观察到实验动物与对照动物之间的明显差异,也不能从形态学方面找到粘膜上皮细胞特有的病变;但也决不能说它是停滞于静止之中,相反。食管粘膜上皮正处于一个 The occurrence and development of esophageal epithelial carcinogenesis is the same as everything else, and it is a constant movement from qualitative change to qualitative change and quality change. Quantitative change refers to the state of motion when it is relatively balanced. When the experimental animal’s esophageal mucosal epithelium was exposed to carcinogens in the early stages, it showed a stable, non-responsive appearance, and actually began to undergo quantitative exercise. Although neither obvious differences between experimental animals nor control animals can be observed from symptoms and signs, nor can epidermis-specific lesions be found in morphological aspects; nevertheless, it cannot be said that it is stagnant in the static state, on the contrary. The esophageal mucosa epithelium is at a