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目的观察补血活血方对慢性乙型肝炎患者肝功能和肝纤维化的影响。方法将166例慢性乙型肝炎患者随机分为对照组(80例)和观察组(86例)。对照组给予甘草酸二铵治疗,观察组在对照组基础上结合补血活血方口服。治疗3个月,观察两组临床疗效、治疗前后肝功能和肝纤维化指标变化情况。结果 1观察组总有效率为93.02%,对照组为81.25%,观察组临床疗效优于对照组(P<0.05);2治疗后,两组肝功能指标均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05);3治疗后,两组肝纤维化指标均较治疗前降低(P<0.05),且观察组低于对照组(P<0.05)。结论补血活血方治疗慢性乙型肝炎疗效确切,具有保护肝功能、抑制肝纤维化作用。
Objective To observe the effect of Buxue Huoxue Fang on liver function and liver fibrosis in patients with chronic hepatitis B. Methods 166 patients with chronic hepatitis B were randomly divided into control group (80 cases) and observation group (86 cases). The control group was treated with diammonium glycyrrhizinate. The observation group was orally administered with the blood-activating and blood-activating prescription on the basis of the control group. After 3 months of treatment, the clinical curative effect, changes of liver function and liver fibrosis index before and after treatment were observed. Results 1 The total effective rate was 93.02% in the observation group and 81.25% in the control group, and the clinical efficacy in the observation group was better than that in the control group (P <0.05). After 2 treatments, the liver function indexes of both groups were lower than those before treatment (P <0.05) , And the observation group was lower than that of the control group (P <0.05). After 3 treatment, the indexes of liver fibrosis in both groups were lower than those before treatment (P <0.05), and the observation group was lower than the control group (P <0.05). Conclusion Buxue Huoxue Fang treatment of chronic hepatitis B curative effect is exact, with the protection of liver function, inhibit liver fibrosis.