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12例中,男9例,女3例,平均年龄42岁。12例患者均为慢性精神分裂症。迟发性运动障碍时间为1～6年,在整个治疗过程中,患者的神经阻滞剂和抗胆碱药物保持不变,泰必利的用量为50～600mg/日,多数在150mg/日左右。12例中用药4个月以上者8例,有4例用药达一年以上。在治疗的不同阶段,采用不自主运动量表(AIMS)评定疗效。结果:治疗6周后,6例各种症状综合评分下降50％以上;8周后,有10例各种症状综合评分下降72％以上,2例减少25％左右,其中1例因停用泰必利改用维生素E治
In 12 cases, 9 males and 3 females, with an average age of 42 years. All 12 patients were chronic schizophrenia. Tardive dyskinesia for 1 to 6 years, throughout the course of treatment, the patient’s nerve blockers and anticholinergic drugs remain unchanged, the amount of tacrolimus 50 ~ 600mg / day, mostly in the 150mg / day or so. Of the 12 cases, 8 cases were treated for more than 4 months, and 4 cases were treated for more than one year. The different stages of treatment, the use of involuntary movement scale (AIMS) to assess the efficacy. Results: After 6 weeks of treatment, the comprehensive scores of various symptoms decreased by more than 50% in 6 cases. After 8 weeks, the comprehensive scores of various symptoms decreased by 72% or more in 2 cases and about 25% in 2 cases, of which 1 was stopped by Thai Will be converted to vitamin E treatment