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通过68例正常人及162例慢性肺疾病患者的肺阻抗血流图(IPR)及其微分图(DPIP)与右心导管同步测定肺动脉平均压(PAMP)进行对比研究,探讨了 IPR 及其 DPIP 指标与 PAMP 的关系,发现 P_2—Y及含 P_2—Y的指标与 PAMP 相关性最好,并能较好地反映病情及 PAMP 的变化;通过多元回归分析择优推荐以下方程作为无创性估测 PAMP 的方法:(1)PAMP=26.6507—144.7508·(P_2—Y)(R=-0.77)、正确性84.0%、敏感性86.4%、正常人假阳性13.2%);(2)PAMP=19.6838+11.7821·(Q-B_1/B_1-Y)-0.903·(B_1—Y)—112.1055·(P_2—Y)(R=0.8122、正确性81.5%、敏感性81.8%、正常人假阳性4.4%)。
The pulmonary arterial pressure (PAMP) measured by IPR and DPIP in 68 normal subjects and 162 patients with chronic lung disease were compared. The results of IPR and DPIP Index and PAMP, and found P_2-Y and P_2-Y-containing indicators of the best correlation with PAMP, and can better reflect the condition and PAMP changes; by multiple regression analysis of preferential recommended the following equation as a non-invasive assessment of PAMP (PAMP = 26.6507-144.7508 · (P 2 -Y) (R = -0.77), correctness 84.0%, sensitivity 86.4%, normal false positive 13.2%); (2) PAMP = 19.6838 + 11.7821 · (Q-B_1 / B_1-Y) -0.903 · (B_1 -Y) -112.1055 · (P_2 -Y) (R = 0.8122, correctness 81.5%, sensitivity 81.8%, normal false positive 4.4%).